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Tubo-ovarian cancer

The risk for a woman to develop tubo-ovarian cancer in their lifetime is estimated at 1-2%. There are tests, such as tumour markers measured in blood serum and imaging methods (ultrasound, CT and MRI), which are abnormal for women with tubo-ovarian cancer. However, tubo-ovarian cancer does not meet the criteria as described above for the…
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Cervical cancer

Cervical Cancer screening is the most successful and widely used example of asymptomatic screening worldwide. The tests used for it are cervical cytology and more recently (in certain health systems) the detection of human papillomavirus high-risk types (HR HPV test). In countries with organized screening systems such as Great Britain and Scandinavia, women who belong…
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Screening for gynaecological cancers

Screening refers to testing an asymptomatic cohort, aiming for early diagnosis and treatment of a disease and improved prognosis. There are clear criteria which need to be met for successful screening to be possible: The disease is common enough within the screened population The disease has recognised precancerous stages with well-understood natural history, slow progression…
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The use of different tests for the detection of HPV infection

A recently published study looked at the role of the messenger RNA (mRNA) HPV test in comparison to HPV DNA test and its place in the British Cervical Screening Programme System.   It is known that HPV mRNA is more specific as it is positive for clinically important infections which carry a higher probability of…
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